Seong-Ho Lee

Education

• Postdoctoral fellow, Pathobiology, University of Tennessee (2007)
• Postdoctoral fellow, Nutritional Biochemistry, University of Wisconsin-Madison (2004)
• Postdoctoral fellow, Growth physiology, Colorado State University (2002)
• Ph. D. Animal Nutrition & Physiology, Korea University (1999)
• M. S. Animal Nutrition, Korea University (1993)
• B. S. Animal Science, Korea University (1991)

Professional Experience

• Professor, Department of Nutrition and Food Science, University of Maryland (2024 Aug -  )
• Associate Professor, Department of Nutrition and Food Science, University of Maryland (2017 Aug - 2024 Aug)
• Assistant Professor, Department of Nutrition and Food Science, University of Maryland (2011 Aug - 2017 Aug)
• Research Assistant Professor, Department of Pathobiology, University of Tennessee (2007 Aug -2011 Aug)

Teaching

• NFSC620 (Diet and Cancer Prevention, 3 credits): 100% involvement (2012 Fall - present)
• NFSC436/636 (Diet and Optimal Human Health, 3 credits): 100% involvement (2013 Spr - present)
• NFSC100 Regular/Hornor/FC (Elements of Nutrition, 3 credits): 25-33% involvement (2013 Fall - 2023 Fall) - Coordinated as a lead instructor (2013 Fall - 2017 Fall).

Research Expertise

• Molecular Nutrition and Biochemistry
• Molecular Carcinogenesis and Chemoprevention
• Diet-related Chronic Disease Prevention
• Nutritional and Environmental Toxicology

Publications * denotes corresponding author and # denotes authors Dr. Lee mentored

• Amarakoon D#, Lee W-J#, Peng J#, Lee S-H* (2024) Identification of translocon-associated protein delta as an oncogene in human colorectal cancer cells. Journal of Cancer Prevention (Accepted).
• Ma P, Jia X, Zhang X, Li Y, He Y, Li T, Wu C, Joo YH, Lee S-H, Meng T, Brozena AH, Li S, Wang Q, Wei C-I, Briber RM, Mao Y, Hu L. (2024) Ion-chelated porous chitosan nanocrystal for highly efficient postharvest preservation. Matter 7:1-14. doi.org/10.1016/j.matt.2024.06.004
• Tamia G#, Amarakoon D#, Wei C-I, Lee S-H* (2024) Evaluation of Humulus lupulus (hops) compound anti-proliferative properties with mechanisms in human colorectal cancer cells. Food Bioscience 57: 103493. doi.org/10.1016/j.fbio.2023.103493
• Lee J#, Lee H-S#, Lee S-H* (2023) Preventive activity of patchouli alcohol against colorectal cancer and diabetes. Journal of Medicinal Food 26(4):255-261. PMID: 37071615
• Amarakoon D#, Lee W-J#, Tamia G#, Lee S-H* (2023) Indole-3-carbinol: occurrence, health-beneficial properties, and cellular/molecular mechanisms. Annual Review of Food Science & Technology 14:347-366. (Review) PMID: 36972159
• Li Y, Wu K, Liu Z, He X, Sun J, Zeng M, Lee, S-H, Wang T, Gao B, Xie Z, Wei C-I, Yu L (2022) Effect of thermal treatments on soluble free, soluble conjugated, and insoluble bound phenolic components and free radical scavenging properties of tomato seeds. ACS Food Science & Technology 2:1631-1638. DOI: https://doi.org/10.1021/acsfoodscitech.2c00228
• Lee H-S#, Amarakoon D#, Tamia G#, Park Y, Smolensky D, Lee S-H* (2022) Pendimethalin induces apoptotic cell death through activating ER stress-mediated mitochondrial dysfunction in human umbilical vein endothelial cells. Food and Chemical Toxicology 168:113370. PMID: 35985363
• Lee H-S#, Song H-J, Park Y, Smolensky D, Lee S-H* (2022) Permethrin inhibits tube formation and viability of endothelial cells. Journal of the Science of Food and Agriculture 102:4079-4085. PMID: 34997580
• Li Y, Liu Z, Tamia GM#, He X, Sun J, Chen P, Lee, S-H, Wang T, Gao B, Xie Z, Yu L (2022) Soluble free, soluble conjugated and insoluble bound phenolics in tomato seeds and their radical scavenging and antiproliferative activities. Journal of Agricultural and Food Chemistry 70(29):9039-9047. PMID:35820155
• Lee H-S#, Tamia G#, Song H-J, Amarakoon D#, Wei C-I, Lee S-H* (2022) Cannabidiol exerts anti-proliferative activity via a cannabinoid receptor 2-dependent mechanism in human colorectal cancer cells. International Immunopharmacology 108:108865. PMID:35598400
• Lee H-S#, Santana ÁL, Peterson J, Yucel U, Perumal R, De Leon J, Lee S-H*, Smolensky D* (2022) Anti-adipogenic activity of high phenolic sorghum brans in pre-adipocytes. Nutrients 14:1493. PMID: 35406112
• Lee W-J#, Lee S-H* (2022) Protocatechuic acid protects hepatocytes against hydrogen peroxide-induced oxidative stress. Current Research in Food Science 5:222-227. PMID: 35106486
• Lee K, Yu H, Shouse S, Kong B, Lee J#, Lee S-H, Ko KS (2021) RNA-Seq reveals different gene expression in liver-specific prohibitin 1 knock-out mice. Frontiers in Physiology 12:717911 PMID: 34539442.
• Lee S-H*, Lee H-S#, Lee J#, Amarakoon D#, Lou Z#, Noronha LE, Herald TJ, Perumal R, Smolensky D (2021) Polyphenol containing sorghum brans exhibit an anti-cancer effect in Apc Min/+ mice treated with dextran sodium sulfate. International Journal of Molecular Sciences 22(15):8286 PMID:34361052
• Lee H-S#, Amarakoon D#, Wei C-I, Choi KY, Smolensky D, Lee S-H* (2021) Adverse effect of polystyrene microplastics (PS-MPs) on tube formation and viability of human umbilical vein endothelial cells. Food and Chemical Toxicology 154:112356 PMID:34157338
• Kang SU, Kim DH, Lee YS, Huang M, Byeon HK, Lee S-H, Baek SJ, Kim C-H (2021) DIM-C-pPhtBu induces lysosomal dysfunction and unfolded protein response-mediated cell death via excessive mitophagy. Cancer Letters 504:23–36 PMID: 33556544
• Amarakoon D#, Lou Z#, Lee W-J#, Smolensky D, Lee S-H* (2021) A mechanistic review: potential chronic disease-preventive properties of sorghum. Journal of the Science of Food and Agriculture 101: 2641–2649. (Review) PMID: 33179254
• Peng M, Lee S-H, Rahaman SO, Biswas D (2020) Dietary probiotic and metabolites improve intestinal homeostasis and prevent colorectal cancer.  Food & Function 11(12):10724-10735. PMID: 33231228
• Lee H-S#, Lee J#, Smolensky D, Lee S-H* (2020) Potential benefits of patchouli alcohol in prevention of human diseases: a mechanistic review. International Immunopharmacology 89(Pt A):107056 (Review). PMID:33039955.
• Lee S-H, Lee J#, Herald T, Cox S, Noronha L, Perumal R, Lee H-S#, Smolensky D (2020) Anti-cancer activity of a novel high phenolic sorghum bran in human colon cancer cells. Oxidative Medicine and Cellular Longevity, 2020:2890536. PMID:33082907.
• Lee J#, Kong B, Lee S-H* (2020) Patchouli alcohol, a compound from Pogostemon cablin, inhibits obesity. Journal of Medicinal Food 23(3):326-334. PMID:31750759
• Song Z, Li Y, Gao B, Lee J#, Wu Y, Sun J, Whent M, Chen P, Lee S-H, Yu L (2020) The chemical composition, antioxidant activity, and antiproliferative activity of selected seed flours. Journal of Food Bioactives 10:77-85. 
• Farias-Pereira R, Savarese J, Yue Y, Lee S-H, Park Y (2020) Fat-lowering effects of isorhamnetin are via NHR-49-dependent pathway in Caenorhabditis elegan. Current Research in Food Science, 2:70-76. PMID:32914113.
• Cox S, Noronha L, Herald T, Bean S, Lee S-H, Perumal R, Wang W, Smolensky D (2019) Evaluation of ethanol-based extraction conditions of sorghum bran bioactive compounds with downstream anti-proliferative properties in human cancer cells. Heliyon, 5(5):e01589. PMID:31111105
• Ha T#, Lee J#, Lou Z#, Lee B-S, Kim C-H, Lee S-H* (2019) Identification of epithelial-specific ETS-1 (ESE-1) as a tumor suppressor and molecular target of green tea compound, EGCG. Molecular Carcinogenesis 58(6):922-932. PMID:30676667 
• Lou Z#, Lee B-S, Ha T#, Xu Y#, Kim H-J, Kim C-H*, Lee S-H* (2018) ESE-1 suppresses the growth, invasion and migration of human NSCLC cells and tumor formation in vivo. Oncology Reports 40(3):1734-1742. PMID:30015943
• Zhang J, Teng Z, Yuan Y, Zeng QZ, Lou Z#, Lee S-H, Wang Q (2018) Development, physicochemical charaterization and cytotoxicity of selenium nanoparticles stabilized by beta-lactoglobulin. International Journal of Biological Macromolecules 107(PtB):1406-1413. PMID:29017880
• Feldman D#, Leahy E#, Lee S-H* (2018) Chemopreventive properties of tolfenamic acid: a mechanistic review. Current Medicinal Chemistry 25(14):1598-1608 (Review). PMID:28413959
• Xu Y#, Lou Z#, Lee S-H* (2017) Arctigenin represses TGF-β-induced epithelial mesenchymal transition in human lung cancer cell. Biochem. Biophys. Res. Commun. 493(2):934-939. PMID:28951214
• Lee J#, Yue Y, Park Y, Lee S-H* (2017) 3,3'-diindolylmethane suppresses adipogenesis using AMPKα-dependent mechanism in 3T3-L1 adipocytes and Caenorhabditis elegans. Journal of Medicinal Food 20(7):646-652. PMID:28459610
• Lee J#, Imm J-Y, Lee S-H* (2017) β-catenin mediates anti-adipogenic and anti-cancer effects of arctigenin in preadipocytes and breast cancer cells. Journal of Agricultural and Food Chemistry 65(12):2513-2520. PMID:28279068
• Lee S-H*, Clark R# (2016) Anti-tumorigenic effects of capsaicin in colon cancer. Journal of Food Chemistry and Nanotechnology 2(4):162-167. DOI:10.17756/jfcn.2016-025
• Shin YS, Kang SU, Park JK, Kim YE, Kim YS, Baek SJ, Lee S-H, Kim C-H (2016) Anti-cancer effect of epigallocatechin-3-gallate (EGCG) in head and neck cancer through repression of transactivation and enhanced degradation of β-catenin. Phytomedicine 23:1344-1355. PMID:27765354
• Silva G, Marins M, Fachin AL, Lee S-H, Baek SJ (2016) Anti-cancer activity of trans-chalcone in osteosarcoma: Involvement of Sp1 and p53. Molecular Carcinogenesis 55(10):1438-1448. PMID:26294168
• Yang X#, Lee S-H* (2016) Identification of ESE1 as a β-catenin binding protein. Anticancer Research 36(6):2697-2704. PMID:27272778
• Ha T#, Lou Z#, Baek SJ, Lee S-H* (2016) Tolfenamic acid downregulates β-catenin in colon cancer. International Immunopharmacology 35:287–293. PMID:27089389
• Min K-W, Lee S-H, Baek SJ (2016) Moonlighting proteins in cancer. Cancer Letters 370:108-116. (Review). PMID:26499805
• Clark R#, Lee S-H* (2016) Anticancer properties of capsaicin against human cancer. Anticancer Research 36(3):837-844. (Review) PMID:26976969
• Jiang X#, Kim K-J#, Ha T#, Lee S-H* (2016) Potential dual role of activating transcription factor 3 in colorectal cancer. Anticancer Research 36(2):509-516. PMID:26851004
• Wong J, Kim Y, Park Y, Lee S-H, Baek SJ, Park Y (2015) Isomer specificity of conjugated linoleic acid on suppression of osteosarcomas.  J. Nature Sci. 1: e67.
• Liu J, Yang P, Shi H, Sun X, Lee S-H, Yu L (2015) A novel Gynostemma pentaphyllum saponin and its adipogenesis inhibitory effect through modulating Wnt/β-catenin pathway and cell cycle in mitotic clonal expansion. Journal of Functional Foods 17: 552-562. DOI:10.1016/j.jff.2015.06.014
• Jeong JB#, Lee J#, Lee S-H* (2015) TCF4 is a molecular target of resveratrol in the prevention of colorectal cancer. International Journal of Molecular Sciences 16:10411-10425. PMID:25961950
• Clark R#, Lee J#, Lee S-H* (2015) Synergistic anti-cancer activity of capsaicin and 3,3’-diindolylmethane in human colorectal cancer. Journal of Agricultural and Food Chemistry 63(17):4297-4304. PMID:25876645
• Shao HJ#, Jeong JB#, Kim K-J#, Lee S-H* (2015) Anti-inflammatory activity of mushroom-derived hispidin through blocking of NF-kB activation. Journal of the Science of Food and Agriculture 95(12):2482-2486. PMID:25355452
• Kim K-J#, Lee J#, Park Y, Lee S-H* (2015) ATF3 mediates anti-cancer activity of trans-10, cis-12-conjugated linoleic acid in human colon cancer cells. Biomolecules&Therapeutics 23(2):134-140. PMID: 25767681
• Shao HJ#, Lou Z#, Jeong JB, Kim K-J#, Lee J#, Lee S-H* (2015) Tolfenamic acid suppresses inflammatory stimuli-mediated activation of NF-ĸB signaling. Biomolecules&Therapeutics 23(1):39-44. PMID:25593642
• Choi J#, Jiang X#, Jeong JB#, Lee S-H* (2014) Anti-cancer activity of protocatechualdehyde in human breast cancer cells. Journal of Medicinal Food 17(8):842-848 PMID:24712725
• Chang JW, Kang SU, Choi JW, Shin YS, Baek SJ, Lee S-H, Kim C-H (2014) Tolfenamic acid induces apoptosis and growth inhibition in anaplastic thyroid cancer: Involvement of nonsteroidal anti-inflammatory drug-activated gene-1 expression and intracellular reactive oxygen species generation. Free Radical Biology and Medicine 67:115-130. PMID:24216474
• Chrysovergis K, Wang X, Kosak J, Lee S-H, Kim JS, Foley JF, Travlos G, Singh S, Baek SJ, Eling TE (2014) NAG-1/GDF15 prevents obesity by increasing thermogenesis, lipolysis and oxidative metabolism. International Journal of Obesity 38(12):1555-1564. PMID:24531647
• Zhang X, Lee S-H, Min K-W, McEntee MF, Jeong JB#, Li Q, Baek SJ (2013) The involvement of endoplasmic reticulum stress in the suppression of colorectal tumorigenesis by tolfenamic acid. Cancer Prevention Research 6(12):1337-1347. PMID:24104354
• Jeong JB#, Yang X#, Clark R#, Choi J#, Baek SJ, Lee S-H* (2013) A mechanistic study of the proapoptotic effect of tolfenamic acid; involvement of NF-κB activation. Carcinogenesis 34:2350-2360. PMID:23784084
• Jeong JB#, Choi J#, Baek SJ, Lee S-H* (2013) Reactive oxygen species mediate tolfenamic acid-induced apoptosis in human colorectal cancer cells. Archives of Biochemistry and Biophysics 537:168-175. PMID:23896514
• Jeong JB#, Choi J#, Lou Z#, Jiang X#, Lee S-H* (2013) Patchouli alcohol, essential oil of Pogostemon cablin, exhibits anti-tumorigenic activity in human colorectal cancer cells. International Immunopharmacology 16:184-190 PMID:23602914
• Jeong JB#, Shin YK#, Lee S-H* (2013) Anti-inflammatory activity of patchouli alcohol in RAW264.7 and HT-29 cells. Food and Chemical Toxicology 55:229-233 PMID:23348408
• Jeong JB#, Lee S-H* (2013) Protocatechualdehyde possesses anti-cancer activity through downregulating cyclin D1 and HDAC2 in human colorectal cancer cells. Biochem. Biophys. Res. Commun 430:381-386. PMID:23159608
• Kang SU, Lee B-S, Lee S-H, Baek SJ, Shin YS, Kim C-H (2013) Expression of NSAID activated gene-1 by EGCG in head and neck cancer: Involvement of ATM-dependent p53 expression. Journal of Nutritional Biochemistry 24:986-999 PMID:23017582
• Kim J, Park Y, Lee S-H, Park Y (2013) trans-10,cis-12 conjugated linoleic acid promotes bone formation by inhibiting adipogenesis by peroxisome proliferator activated receptor-γ dependent mechanisms and by directly enhancing osteoblastogenesis from bone marrow mesenchymal stem cells. Journal of Nutritional Biochemistry 24:672–679. PMID:22832076
• Kang SU, Shin YS, Hwang HS, Baek SJ, Lee S-H, Kim C-H (2012) Tolfenamic acid induces apoptosis and growth inhibition in head and neck cancer: Involvement of NAG-1 expression. PLoS ONE 2012;7(4):e34988. PMID:22536345
• Lee S-H, Min KW, Zhang X, Baek SJ (2013) 3,3'-diindolylmethane induces activating transcription factor 3 (ATF3) via ATF4 in human colorectal cancer cells. Journal of Nutritional Biochemistry 24:664-671 PMID:22819556
• Nualsanit T, Rojanapanthu P, Gritsanapan W, Lee S-H, Lawson D and Baek SJ (2012) Damnacanthal, a Noni component, exhibits anti-tumorigenic activity in human colorectal cancer cells. Journal of Nutritional Biochemistry 23:915-923 PMID:21852088
• Lee S-H*, Richardson RL, Dashwood RH, Baek SJ (2012) Capsaicin represses transcriptional activity of β-catenin in human colorectal cancer cells. Journal of Nutritional Biochemistry 23:646-655. PMID:21764279
• Margraves C, Kihm K, Yoon SY, Choi CK, Lee S-H, Liggett J, Baek SJ (2011) Simultaneous measurements of cytoplasmic viscosity and intracellular vesicle sizes for live human brain cancer cells. Biotechnology & bioengineering 108: 2504–2508. PDIM:21520025
• Krisanapun C, Lee S-H, Peungvicha P, Temsiririrkkul R, Baek SJ (2011) Antidiabetic activities of abutilon indicum (L.) sweet are mediated by enhancement of adipocyte differentiation and activation of the GLUT1 promoter. Evidence-based Complementary and Alternative Medicine. 2011:167684. PMID:21603234
• Whitlock NC, Bahn JH, Lee S-H, Eling TE, Baek SJ (2011) Resveratrol-induced apoptosis is mediated by early growth response-1, krüppel-like factor 4, and activating transcription factor 3. Cancer Prevention Research 4:116–127. PMID:21205742
• Kim C-H, Bahn JH, Lee S-H, Kim G-Y, Jun S, Lee K, Baek SJ (2010) Induction of cell growth arrest by atmospheric non-thermal plasma in colorectal cancer cells. Journal of Biotechnology 150:530–538. PMID: 20959125
• Zhong Y, Krisanapun C, Lee S-H, Nualsanit T, Sams C, Peungvicha P, Baek SJ (2010) Molecular targets of apigenin in colorectal cancer cells: Involvement of p21, NAG-1 and p53. Eur J Cancer. 46:3365-3374. PMID: 20709524
• Lee S-H, Bahn JH, Whitlock NC, Baek SJ (2010) Activating transcription factor 2 (ATF2) controls tolfenamic acid-induced ATF3 expression via MAP kinase pathways. Oncogene 29: 5182–5192. PMID: 20581861
• Cekanova M, Lee S-H, McEntee MF, Baek SJ (2010) MCC-555-induced NAG-1 expression is mediated in part by KLF4. Eur. J. Pharmacol. 637: 30–37. PMID: 20385121
• Lee S-H, Krisanapun C, Baek SJ. (2010) NSAID-activated gene-1 as a molecular target for capsaicin-induced apoptosis through a novel molecular mechanism involving GSK3β, C/EBPβ, and ATF3. Carcinogenesis 31(4):719-728. PMID: 20110283
• Choi CK, Sukhthankar M, Kim C-H, Lee S-H, English A, Kihm KD, Baek SJ (2010) Cell adhesion property affected by cyclooxygenase and lipoxygenase: Opto-electric approach. Biochem. Biophys. Res. Commun. 391:1385-1389. PMID: 20026301  
• Cekanova M, Lee S-H, Donnell RL, Sukhthankar M, Eling TE, Fischer SM, Baek SJ (2009) Nonsteroidal Anti-inflammatory Drug-Activated Gene-1 Expression Inhibits Urethane-Induced Pulmonary Tumorigenesis in Transgenic Mice. Cancer Prevention Research 2(5):450-458. PMID: 19401523
• Iguchi G, Chrysovergis K, Lee S-H, Baek SJ, Langenbach R, Eling TE (2009) A reciprocal relationship exists between non-steroidal anti-inflammatory drug-activated gene-1 (NAG-1) and cyclooxygenase-2. Cancer Letter 282(2):152-158. PMID: 19375854
• Lee S-H, Bahn JH, Choi CK, Whitlock NC, English AE, Safe S, Baek SJ (2008) ESE-1/EGR-1 pathway plays a role in tolfenamic acid-induced apoptosis in colorectal cancer cells. Molecular Cancer Therapeutics 7(12):3739-3750. PMID: 19074849
• Sukhthankar M, Yamaguchi K, Lee S-H, McEntee MF, Eling TE, Hara Y, Baek SJ (2008) A green tea component suppresses post-translational expression of basic fibroblast growth factor in colorectal cancer. Gastroenterology 134:1972-1980. PMID: 18549879
• Lee S-H, Cekanova M, Baek SJ (2008) Multiple mechanisms are involved in 6-gingerol-induced cell cycle arrest and apoptosis in human colorectal cancer cells. Molecular Carcinogenesis 47:197-208. PMID: 18058799
• Cho K-N, Sukhthankar M, Lee S-H, Yoon J-H, Baek SJ (2007) Green tea catechin epicatechin gallate induces tumor suppressor protein ATF3 via EGR-1 activation. Eur J Cancer 43:2404-2412. PMID: 17764926
• Lim YC$, Lee S-H$, Song MH, Yamaguchi K, Yoon J-H, Choi EC, Baek SJ (2006) Growth inhibition and apoptosis by (-)-epicatechin gallate are mediated by cyclin D1 suppression in head and neck squamous carcinoma cells. Eur J Cancer 42:3260-3266. PMID: 17045795 $equally contributed
• Baek SJ, Okazaki R, Lee S-H, Martinez J, Kim J-S, Yamaguchi K, Mishina Y, Martin DW, Shoieb A, McEntee MF, Eling TE (2006) Nonsteroidal anti-inflammatory drug activated gene-1 over-expression in transgenic mice suppresses intestinal neoplasia. Gastroenterology 131(5):1553-1560. PMID: 17101328
• Yamaguchi K, Lee S-H, Eling TE, Baek SJ (2006) A novel peroxisome proliferator-activated receptor γ ligand, MCC-555, induces apoptosis via posttranscriptional regulation of NAG-1 in colorectal cancer cells. Molecular Cancer Therapeutics 5(5):1352-1361. PMID: 16731769
• Lee S-H, Yamaguchi K, Kim J-S, Eling  TE, Safe S, Park Y, Baek SJ (2006) Conjugated linoleic acid stimulates an anti-tumorigenic protein NAG-1 in an isomer specific manner. Carcinogenesis 27(5):972-981. PMID: 16286461
• Yamaguchi K, Lee S-H, Kim J-S, Wimalasena J, Kitajima S, Baek SJ (2006) Activating transcription factor 3 and early growth response-1 are the novel targets of LY294002 in a PI3K independent pathway. Cancer Research. 66:2376-2384. PMID: 16489044  
• Kim J-H, Yamaguchi K, Lee S-H, Tithof, PK, Sayler GS, Yoon J-H, Baek SJ (2005) Evaluation of polycyclic aromatic hydrocarbons in the activation of early growth response-1 and peroxisome proliferator activated receptors. Toxicol. Sci. 85:585-593. PMID: 15716483
• Lee S-H, Kim J-S, Yamaguchi K, Eling TE, Baek SJ (2005) Indole-3-carbinol and 3,3'-diindolylmethane induce expression of NAG-1 in a p53 independent manner. Biochem. Biophys. Res. Commun. 328:63-69. PMID: 15670751
• Baek SJ, Kim J-S, Moore SM, Lee S-H, Martinez J, Eling TE (2005) Cyclooxygenase inhibitors induce the expression of the tumor suppressor gene EGR1, which results in the up-regulation of NAG-1, an anti-tumorigenic protein. Mol. Pharmacol. 67(2):356-364. PMID: 15509713   
• Baek SJ, Kim J-S, Jackson FR, Eling TE, McEntee MF, Lee S-H (2004) Epicatechin gallate-induced expression of NAG-1 is associated with growth inhibition and apoptosis in colon cancer cells. Carcinogenesis 25(12):2425-2432. PMID: 15308587
• Yamaguchi K, Lee S-H, Eling TE, Baek SJ (2004) Identification of nonsteroidal anti-inflammatory drug-activated gene (NAG-1) as a novel downstream target of phosphatidylinositol 3-kinase/AKT/GSK-3β pathway. J. Biol. Chem. 279(48): 49617-49623. PMID: 15377673
• Dobrzyn A, Dobrzyn P, Lee S-H, Miyazaki M, Cohen P, Asilmaz E, Hardie DH, Friedman JM, Ntambi JM (2005) Stearoyl-CoA desaturase 1 deficiency reduces ceramide synthesis by down-regulating serine palmitoyltransferase and increasing b-oxidation in skeletal muscle. Am. J. Physiol. Endocrinol. Metab. 288:E599-607. PMID: 15562249
• Rahman SM, Dobrzyn A, Lee S-H, Dobrzyn P, Miyazaki M, Ntambi JM (2005) Stearoyl-CoA desaturase 1 deficiency increases insulin signaling and glycogen accumulation in brown adipose tissue. Am. J. Physiol. Endocrinol. Metab. 288:E381-387. PMID: 15494611
• Lee S-H, Dobrzyn A, Dobrzyn P, Rahman SM, Miyazaki M, Ntambi JM (2004) Lack of stearoyl-CoA desaturase 1 upregulates basal thermogenesis, but causes hypothermia in cold environment. J. Lipid Res. 45(9):1674-1682. PMID: 15210843
• Miyazaki M, Dobrzyn A, Sampath H, Lee S-H, Man WC, Chu K, Peters JM, Gonzalez FJ, Ntambi JM (2004) Reduced adiposity and liver steatosis by stearoyl-CoA desaturase deficiency are independent of peroxisome proliferator-activated receptor-α. J. Biol. Chem. 279(33):35017-35024. PMID: 15180999
• Rahman SM, Dobrzyn A, Dobrzyn P, Lee S-H, Miyazaki M, Ntambi JM (2003) Stearoyl-CoA desaturase 1 deficiency elevates insulin signaling components and downregulates protein-tyrosine phosphatase 1B in muscle. Proc. Natl. Acad. Sci. USA. 100(19):11110-11115. PMID: 12960377
• Lee S-H, Hossner KL (2002) Effects of bovine colostral ultrafiltrates on growth and differentiation of 3T3-L1 preadipocytes. Biotechnol Appl Biochem. 36:205-212. PMID: 12452804
• Lee S-H, Hossner KL (2002) Coordinate regulation of ovine adipose tissue gene expression by propionate. J. Anim. Sci. 80(11):2840-2849. PMID: 12462251
• Lee S-H, Engle TE, Hossner KL (2002) Effects of dietary copper on the expression of lipogenic genes and metabolic hormones in steers. J. Anim. Sci. 80(7):1999-2005. PMID: 12162670
• Lee S-H, Kim KD, Ko KS, Son YS (2000) Retinoic acid level and function of porcine thyroid cells in vitro. Korean J. Anim. Sci. Technol. 42(2):165-172.
• Lee S-H, Hong SH, Son YS (1999) Studies on the substances modulating nitrate and nitrite reduction by rumen microbes. Korean J. Anim. Nutr. Feed. 23(5):411-418.
• Son Y-S, Kim S-H, Hong S-H, Lee S-H (1998) Effect of feeding bentonite and granite porphyry on ruminal buffering activity and fermentation pattern. Korean J. Dairy Sci. 20(1):21-32.
• Han H-C, Lee S-H, Son Y-S (1994) In situ and in vitro evaluations of some feed proteins heat-treated by different processing methods. Korean J. Anim. Nutr. Feed 18(6):491-498.
• Son Y-S, Yu B-W, Han H-C, Lee S-H, Lee C-J, Kim K-S (1994) A field study on the ruminal pH of lactating cows according to feeding system in Korea. Korean J. Dairy Sci. 16(4):326-334.
• Lee S-H, Son Y-S (1993) Characteristics of nitrate reduction by rumen microorganism and responses of host animal to prolonged nitrate intake. Korean J. Dairy Sci. 15(4):261-270.